Baricitinib, a New Oral JAK1/JAK2 Inhibitor for Psoriasis
Efficacy of baricitinib at 12 weeks in this phase II trial was comparable to that of many other psoriatic skin disease medications.
View ArticleFrequency of Residual Melanoma in Wide Local Excision Specimens After...
The frequency of residual lentigo maligna suggests a benefit from 100% margin control during re-excision with Mohs surgery.
View ArticleSubstituting One Smoothened Inhibitor for Another Did Not Forestall Resistance
But generalizability is limited.
View ArticleWhat Say? (FREE)
The International League of Dermatological Societies presents a revised glossary for the description of cutaneous lesions.
View ArticleDoes Elongating the Leading Edge of a Rotation Flap Closure Reduce Tension?
When such flaps have elongated leading edges, tip tension may be reduced, with commensurate reduction in the likelihood of tip necrosis.
View ArticleVulvar Squamous Cell Carcinoma and Recurrences
Increased recurrence and likelihood of death is associated with non–HPV-related versus HPV-related vSCC.
View ArticleRheumatoid Arthritis, Anti–Tumor Necrosis Factor Treatment, and Skin Cancer
Patients about to start TNF-inhibitor treatment should be counseled that these agents only modestly increase the probability of developing NMSCs
View ArticleIncidence and Survival of Primary Dermatofibrosarcoma Protuberans in the...
This study provides the best available data regarding the incidence, risk factors, and mortality associated with DFSP.
View ArticleConsider Using TMP/SMX After Draining Uncomplicated Abscesses (FREE)
Trimethoprim–sulfamethoxazole led to a higher rate of cure, but even without antibiotics, the majority of abscesses resolved.
View ArticlePrimary Cutaneous Follicle Center Lymphoma and Its Molecular Landscape
New research alerts us to a PCFCL subset affecting mainly head and neck with genetic alteration [t(14;18)] and immunoprofile (CD10+, BCL-6+, BCL2+, STMN+) similar to the nodal type, but with a benign...
View ArticleBe Aware of Erosive Lichen Planus as Mimicker of Dysplasia in the Vulva (FREE)
Histologic overlap between differentiated vulvar intraepithelial neoplasia and erosive lichen planus may require a multidisciplinary conference for resolution.
View ArticleThe Use of Molecular Studies for Diagnosis of Undifferentiated Tumors (FREE)
Absent other diagnostic tools, BRAF/NRAS/KIT genotyping appears to provide viable surrogate markers for diagnosis of malignant melanoma in undifferentiated tumors.
View ArticleIncreased Risk for Cardiovascular Adverse Events in Patients with...
HS is a chronic inflammatory process, and patients also have increased frequency of obesity and diabetes, features favoring enhanced cardiovascular risk.
View ArticleVerrucous Carcinoma of the Vulva (FREE)
Surgical excision is the treatment of choice for vVC.
View ArticleBelieve the Parents: QOL in Families with Young Children with Eczema (FREE)
We should listen to parents' assessment of their children's atopic dermatitis severity.
View ArticleEffective Sun Safety in Children: A Randomized Controlled Trial of a...
Interactive interventions produced measurable results.
View ArticleHydroxychloroquine Blood Levels May Be Helpful in Patients with...
Increasing the hydroxychloroquine dose to achieve adequate levels produced clinical response.
View ArticleDoes Childhood Vitiligo Differ When Halo Nevi Are Present? (FREE)
HN are much more common in vitiligo patients, especially children, but they do not significantly alter treatment response or risk for disease progression.
View ArticleMelatonin for Childhood Atopic Dermatitis and Sleep Disturbance (FREE)
A well-conducted randomized, double-blind trial suggests that melatonin may improve both.
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